Download e-book for kindle: Apoptosis, Senescence and Cancer by David A. Gewirtz, Shawn E. Holt, Steven Grant

By David A. Gewirtz, Shawn E. Holt, Steven Grant

ISBN-10: 1617376213

ISBN-13: 9781617376214

This publication presents perception into tested practices and examine into apoptosis and senescence. the amount completely examines novel and rising ideas and learn within the fields of mobile loss of life pathways, senescence progress arrest, medicinal drugs and resistance, DNA harm reaction, and different issues that also carry mysteries for researchers. In overall, this quantity offers uncomplicated scientists and clinicians with a deeper and extra entire realizing of the mobile responses of malignancies which can verify the effectiveness of remedy, either within the preliminary phases of the affliction in addition to in sickness recurrence.

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Extra info for Apoptosis, Senescence and Cancer

Example text

Earnshaw WC, Martins LM, Kaufmann SH. Mammalian caspases: structure, activation, substrates and functions during apoptosis. Annu Rev Biochem 1999; 68:383–424. 5. Fischer U, Janicke RU, Schulze-Osthoff K. Many cuts to ruin: a comprehensive update of caspase substrates. Cell Death Differ 2003; 10(1):76–100. 6. Li X, Gong J, Feldman E, Seiter K, Traganos F, Darzynkiewicz Z. Apoptotic cell death during treatment of leukemias. Leuk Lymphoma 1994; 13(Suppl 1):65–70. 7. Seiter K, Feldman EJ, Halicka HD, et al.

Mitochondria: releasing power for life and unleashing the machineries of death. Cell 2003; 112:481–90. 65. Jiang X, Wang X. Cytochrome C-mediated apoptosis. Annu Rev Biochem 2004; 73:87–106. 66. Anflous K, Armstrong DD, Craigen WJ. Altered mitochondrial sensitivity for ADP and maintenance of creatine-stimulated respiration in oxidative striated muscles from VDAC1-deficient mice. J Biol Chem 2001; 276:1954–60. 67. Graham BH, Waymire KG, Cottrell B, Trounce IA, MacGregor GR, Wallace DC. A mouse model for mitochondrial myopathy and cardiomyopathy resulting from a deficiency in the heart/muscle isoform of the adenine nucleotide translocator.

Acehan D, Jiang X, Morgan DG, Heuser JE, Wang X, Akey CW. Three-dimensional structure of the apoptosome. Implications for assembly, procaspase-9 binding, and activation. Mol Cell 2002; 9(2):423–32. 57. Hill MM, Adrain C, Duriez PJ, Creagh EM, Martin SJ. Analysis of the composition, assembly kinetics and activity of native Apaf-1 apoptosomes. EMBO J 2004; 23(10):2134–45. 58. Shi Y. Caspase activation: revisiting the induced proximity model. Cell 2004; 117:855–8. 59. Liu X, Kim CN, Yang J, Jemmerson R, Wang X.

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Apoptosis, Senescence and Cancer by David A. Gewirtz, Shawn E. Holt, Steven Grant


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