By Arthur M. Silverstein
Written by means of an immunologist, A background of Immunology traces the concept that of immunity from precedent days as much as the current day, interpreting how altering recommendations and applied sciences have affected the process the technological know-how. It indicates how the personalities of scientists or even political and social elements encouraged either concept and perform within the box. With attention-grabbing tales of medical disputes and transferring medical developments, every one bankruptcy examines a huge part of this self-discipline that has been so crucial to the advance of recent biomedicine. With its biographical dictionary of significant scientists and its lists of vital discoveries and books, this quantity will give you the so much whole historic reference within the field.
- Written in a chic variety by way of long-time practising immunologist
- Discusses the altering theories and applied sciences that guided the field
- Tells of the fascinating disputes between popular scientists
- Lists all of the vital discoveries and books within the field
- Explains intimately the numerous Nobel prize-winning contributions of immunologists
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Extra info for A History of Immunology, Second Edition
Paul de Kruif goes too far perhaps in suggesting in his book Microbe Hunters19 that this epic struggle in immunology contributed to the start of World War I, but it does seem probable that, in a minor way at least, it did represent one of the continuing reverberations of the Franco-Prussian War of 1870. Cellular vs humoral immunity The early debate Ilya (later Elie) Metchnikoff was born in the Steppe region of Little Russia in 1845. He studied invertebrate zoology in both Russia and Germany, and developed a keen interest in invertebrate embryology while working at Naples with the great Russian embryologist Kovalevsky.
Discovery of bacterial agglutination38 provided still another convincing demonstration of the importance of humoral antibody in defense against infection. It only remained for Ehrlich to provide a theoretical formulation in his side-chain concept of the functions of antibody, antigen, and complement39 to make the antibody the principal object of interest to almost all immunologists. This was helped in no small measure by the pictures which Ehrlich published to illustrate his side-chain theory – pictures that made it easier to believe that antibodies and complement were ‘‘real substances’’ with comprehensible receptors and simple modes of action.
The Adoption of Inoculation for Smallpox in England and France, Philadelphia, University of Pennsylvania Press, 1959, p. 244. , The Analysis of Inoculation, London, 1754, p. 41. , An Introduction to the History of Medicine, Philadelphia, Saunders, 1917. , A History of Medicine, New York, Knopf, 1947. , ‘De Magnetica Vulnerum Curatione’, in Sylvestre Rattray, Theatrum Sympatheticum Auctum, Nu¨rnberg, 1662, p. 477. , Anthropologia Nova: Or, a New System of Anatomy, Vol. I, London, 1707, p. 25. , An Essay on Contagious Diseases, York, 1721.
A History of Immunology, Second Edition by Arthur M. Silverstein